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Proteintech
PPIF Polyclonal Antibody
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Product Details
18466-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PPIF-Specific Fusion Protein Ag13151 (1-207 aa encoded by BC005020)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is immunized with full length gene PPIF and absorbed by PPIA. So this antibody is specific to PPIF.
Immunogen sequence: MLALRCGSR WLGLLSVPRS VPLRLPAARA CSKGSGDPSS SSSSGNPLVY LDVDANGKPL GRVVLELKAD VVPKTAENFR ALCTGEKGFG YKGSTFHRVI PSFMCQAGDF TNHNGTGGKS IYGSRFPDEN FTLKHVGPGV LSMANAGPNT NGSQFFICTI KTDWLDGKHV VFGHVKEGMD VVKKIESFGS KSGRTSKKIV ITDCGQLS (1-207 aa encoded by BC005020)
Target Information
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cyclophilin 3; Cyclophilin D; Cyclophilin F; CyP-D; CyP-M; Mitochondrial cyclophilin; mitochondrial Cyclophilin D; mitochondrial peptidyl-prolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase F; Peptidyl-prolyl cis-trans isomerase F, mitochondrial; peptidyl-prolyl cis-trans isomerase, mitochondrial; PPIase F; Rotamase F; unnamed protein product
Gene Aliases: AW457192; CyP-D; CyP-F; CyP-M; CYP3; CypD; PPIase; PPIF
UniProt ID: (Human) P30405, (Rat) P29117, (Mouse) Q99KR7
Entrez Gene ID: (Human) 10105, (Rat) 282819, (Mouse) 105675
response to ischemia
protein folding
apoptotic process
response to oxidative stress
mitochondrion organization
apoptotic mitochondrial changes
regulation of proton-transporting ATPase activity, rotational mechanism
programmed cell death
negative regulation of apoptotic process
regulation of mitochondrial membrane permeability
mitochondrial depolarization
muscle structure development
necroptotic process
cellular response to hydrogen peroxide
cellular response to arsenic-containing substance
cellular response to calcium ion
negative regulation of release of cytochrome c from mitochondria
negative regulation of oxidative phosphorylation
skeletal muscle fiber differentiation
regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
mitochondrial outer membrane permeabilization involved in programmed cell death
negative regulation of intrinsic apoptotic signaling pathway
protein peptidyl-prolyl isomerization
regulation of necrotic cell death
negative regulation of ATPase activity
regulation of apoptotic process
positive regulation of release of cytochrome c from mitochondria
negative regulation of oxidative phosphorylation uncoupler activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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