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Proteintech
PPP1R15B Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-14634
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PPP1R15B fusion protein Ag6213
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: TTEVPLALEE ESPSEGCPSS EIPMEKEPGE GRISVVDYSY LEGDLPISAR PACSNKLIDY ILGGASSDLE TSSDPEGEDW DEEAEDDGFD SDSSLSDSDL EQDPEGLHLW NSFCSVDPYN PQNFTATIQT AARIVPEEPS DSEKDLSGKS DLENSSQSGS LPETPEHSSG EEDDWESSAD EAESLKLWNS FCNSDDPYNP LNFKAPFQTS GENEKGCRDS ETPSESIVAI SECHTLLSCK VQLLGSQESE CPDSVQRDVL SGGRHTHVKR KKVTFLEEVT EYYISGDEDR KGPWEEFARD GCRFQKRIQE TEDAIGYCLT FEHRERMFNR LQGTCFKGLN VLKQC
Target Information
Maintains low levels of EIF2S1 phosphorylation in unstressed cells by promoting its dephosphorylation by PP1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Constitutive repressor of eIF2alpha phosphorylation; CReP; Protein phosphatase 1 regulatory subunit 15B; protein phosphatase 1, regulatory (inhibitor) subunit 15B; unnamed protein product
Gene Aliases: 1810033K10Rik; AI606441; C530022L24Rik; CREP; MSSGM2; PPP1R15B
UniProt ID: (Human) Q5SWA1, (Mouse) Q8BFW3
Entrez Gene ID: (Human) 84919, (Rat) 304799, (Mouse) 108954
negative regulation of protein phosphorylation
regulation of translation
response to oxidative stress
ER overload response
response to endoplasmic reticulum stress
response to hydrogen peroxide
regulation of protein metabolic process
negative regulation of PERK-mediated unfolded protein response
dephosphorylation
regulation of translational initiation
peptidyl-serine dephosphorylation
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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