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Proteintech
PPP5C Polyclonal Antibody
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Product Details
11715-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PPP5C Fusion Protein Ag2288 (150-500 aa encoded by BC001970)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RAIAGDEHK RSVVDSLDIE SMTIEDEYSG PKLEDGKVTI SFMKELMQWY KDQKKLHRKC AYQILVQVKE VLSKLSTLVE TTLKETEKIT VCGDTHGQFY DLLNIFELNG LPSETNPYIF NGDFVDRGSF SVEVILTLFG FKLLYPDHFH LLRGNHETDN MNQIYGFEGE VKAKYTAQMY ELFSEVFEWL PLAQCINGKV LIMHGGLFSE DGVTLDDIRK IERNRQPPDS GPMCDLLWSD PQPQNGRSIS KRGVSCQFGP DVTKAFLEEN NLDYIIRSHE VKAEGYEVAH GGRCVTVFSA PNYCDQMGNK ASYIHLQGSD LRPQFHQFTA VPHPNVKPMA YANTLLQLGM M (150-500 aa encoded by BC001970)
Target Information
This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ANP receptor; FLJ36922; FLJ55954; OTTHUMP00000165834; PP-T; PP5; PPT; protein phosphatase 5, catalytic subunit; Protein phosphatase T; Serine/threonine-protein phosphatase 5
Gene Aliases: AU020526; PP5; PPP5; PPP5C; PPT
UniProt ID: (Human) P53041, (Rat) P53042, (Mouse) Q60676
Entrez Gene ID: (Human) 5536, (Rat) 65179, (Mouse) 19060
G-protein alpha-subunit binding
RNA binding
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
signal transducer activity
protein binding
ATP binding
microtubule binding
lipid binding
heat shock protein binding
identical protein binding
ADP binding
metal ion binding
hydrolase activity
protein phosphatase
MAPK cascade
negative regulation of protein phosphorylation
DNA repair
transcription, DNA-templated
protein dephosphorylation
mitotic nuclear division
response to lead ion
histone dephosphorylation
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to morphine
protein heterooligomerization
cellular response to hydrogen peroxide
cellular response to cadmium ion
negative regulation of neuron death
positive regulation of glucocorticoid receptor signaling pathway
signal transduction
dephosphorylation
protein oligomerization
negative regulation of cell death
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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