PA5-28720 targets PRAM1 in WB applications and shows reactivity with Human samples.
The PA5-28720 immunogen is synthetic peptide corresponding to a region within amino acids 653 and 718 of Human PRAM1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).
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Protein Aliases: PML-RAR; PML-RARA target gene encoding an Adaptor Molecule-1; PML-RARA-regulated adapter molecule 1; PRAM
Gene Aliases: PML-RAR; PRAM-1; PRAM1
UniProt ID: (Human) Q96QH2
Entrez Gene ID: (Human) 84106