Immunogen sequence: QLPPMDPKLLK QLRKAEKAER EFRKKFKFEG EIVVHTKMMI DPNAKTRRGG GKHLGIRRGE ILEVIEFTSN EEMLCRDPKG KYGYVP
Highest antigen sequence identity to the following orthologs - mouse 93%, rat 91%.
The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC39864; PML-RAR; PML-RARA regulated adaptor molecule 1; PML-RARA target gene encoding an Adaptor Molecule-1; PML-RARA-regulated adapter molecule 1; PRAM; PRAM-1 protein
Gene Aliases: PML-RAR; PRAM-1; PRAM1
UniProt ID: (Human) Q96QH2
Entrez Gene ID: (Human) 84106