FIGURE: 1 / 2
Peptide sequence: GPFAGEKRMP EDLDENMDYR LMWEVRGSKG EVLYILDATN PRHSNWLRFV
Sequence homology: Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
PRDM5, a novel member of PR domain protein family, contains a PR-domain at the -NH2 terminus followed by 16 zinc finger motifs. It is found to have a role in cell differentiation and tumorigenesis. Reports suggest PRDM5 causes G2/M arrest and apoptosis upon infection of tumor cells and has been found to be silenced in breast, ovarian and lung cancers, suggesting a potential clinical significance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PR domain containing 5; PR domain zinc finger protein 5; PR domain-containing protein 5
Gene Aliases: BCS2; PFM2; PRDM5
UniProt ID: (Human) Q9NQX1
Entrez Gene ID: (Human) 11107
Molecular Function: C2H2 zinc finger transcription factor