PA5-34853 targets Peroxiredoxin 4 in IHC (P) and WB applications and shows reactivity with Human and Mouse samples.
The PA5-34853 immunogen is recombinant protein fragment contains a sequence corresponding to a region within amino acids 25 and 216 (Q13162) of peroxiredoxin 4.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
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Protein Aliases: Antioxidant enzyme AOE372; AOE37-2; epididymis secretory sperm binding protein Li 97n; Peroxiredoxin IV; Peroxiredoxin-4; PRX 4; PRX IV; PRX-4; Prx-IV; PRX4; thioredoxin peroxidase (antioxidant enzyme); Thioredoxin peroxidase AO372; Thioredoxin-dependent peroxide reductase A0372
Gene Aliases: AOE37-2; AOE372; HEL-S-97n; PRDX4; PRX-4; Prx-iv; Prx4; TRANK