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Abnova
PRMT7 Polyclonal Antibody, MaxPab™
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Product Details
H00054496-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PRMT7 (NP_061896.1, 1 a.a. approximately 692 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKIFCSRANP TTGSVEWLEE DEHYDYHQEI ARSSYADMLH DKDRNVKYYQ GIRAAVSRVK DRGQKALVLD IGTGTGLLSM MAVTAGADFC YAIEVFKPMA DAAVKIVEKN GFSDKIKVIN KHSTEVTVGP EGDMPCRANI LVTELFDTEL IGEGALPSYE HAHRHLVEEN CEAVPHRATV YAQLVESGRM WSWNKLFPIH VQTSLGEQVI VPPVDVESCP GAPSVCDIQL NQVSPADFTV LSDVLPMFSI DFSKQVSSSA ACHSRRFEPL TSGRAQVVLS WWDIEMDPEG KIKCTMAPFW AHSDPEEMQW RDHWMQCVYF LPQEEPVVQG SALYLVAHHD DYCVWYSLQR TSPEKNERVR QMRPVCDCQA HLLWNRPRFG EINDQDRTDR YVQALRTVLK PDSVCLCVSD GSLLSVLAHH LGVEQVFTVE SSAASHKLLR KIFKANHLED KINIIEKRPE LLTNEDLQGR KVSLLLGEPF FTTSLLPWHN LYFWYVRTAV DQHLGPGAMV MPQAASLHAV VVEFRDLWRI RSPCGDCEGF DVHIMDDMIK RALDFRESRE AEPHPLWEYP CRSLSEPWQI LTFDFQQPVP LQPLCAEGTV ELRRPGQSHA AVLWMEYHLT PECTLSTGLL EPADPEGGCC WNPHCKQAVY FFSPAPDPRA LLGGPRTVSY AVEFHPDTGD IIMEFRHADT PD
Target Information
Arginine methylation is an irreversible post translational modification which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These proteins include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [Myelin basic protein]-arginine N-methyltransferase PRMT7; FLJ10640; Histone-arginine N-methyltransferase PRMT7; myelin basic protein-arginine N-methyltransferase; PRMT-7; Protein arginine N-methyltransferase 7
Gene Aliases: KIAA1933; PRMT7
UniProt ID: (Human) Q9NVM4
Entrez Gene ID: (Human) 54496
histone-arginine N-methyltransferase activity
S-adenosylmethionine-dependent methyltransferase activity
protein-arginine N-methyltransferase activity
[myelin basic protein]-arginine N-methyltransferase activity
protein-arginine omega-N monomethyltransferase activity
protein-arginine omega-N asymmetric methyltransferase activity
protein-arginine omega-N symmetric methyltransferase activity
histone binding
ribonucleoprotein complex binding
histone methyltransferase activity (H4-R3 specific)
protein modifying enzyme
spliceosomal snRNP assembly
regulation of gene expression by genetic imprinting
transcription, DNA-templated
regulation of transcription, DNA-templated
histone methylation
peptidyl-arginine methylation
peptidyl-arginine methylation, to symmetrical-dimethyl arginine
peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
cell differentiation
histone arginine methylation
DNA methylation involved in gamete generation
regulation of protein binding
histone H4-R3 methylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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