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Proteintech
PROS1 Polyclonal Antibody
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Product Details
16910-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PROS1 Fusion Protein Ag10539 (328-676 aa encoded by BC015801)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DFRTYDSEG VILYAESIDH SAWLLIALRG GKIEVQLKNE HTSKITTGGD VINNGLWNMV SVEELEHSIS IKIAKEAVMD INKPGPLFKP ENGLLETKVY FAGFPRKVES ELIKPINPRL DGCIRSWNLM KQGASGIKEI IQEKQNKHCL VTVEKGSYYP GSGIAQFHID YNNVSSAEGW HVNVTLNIRP STGTGVMLAL VSGNNTVPFA VSLVDSTSEK SQDILLSVEN TVIYRIQALS LCSDQQSHLE FRVNRNNLEL STPLKIETIS HEDLQRQLAV LDKAMKAKVA TYLGGLPDVP FSATPVNAFY NGCMEVNING VQLDLDEAIS KHNDIRAHSC PSVWKKTKNS (328-676 aa encoded by BC015801)
Target Information
Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 µg/mL, with a half-life of approximately two days. About 40% of Protein S in plasma is in a free form, whereas 60% is complexed with C4b-binding Protein (C4BP). Only the free Protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Preproprotein S; PROS 1; Protein S alpha; protein Sa; proteinS; PS 21; PS 22; PS 23; PS 24; PS 25; PS 26; PS26; vitamin K-dependent plasma protein S; Vitamin K-dependent protein S
Gene Aliases: AW214361; PROS; PROS1; PS21; PS22; PS23; PS24; PS25; PSA; THPH5; THPH6
UniProt ID: (Human) P07225, (Mouse) Q08761
Entrez Gene ID: (Human) 5627, (Mouse) 19128
platelet degranulation
signal peptide processing
ER to Golgi vesicle-mediated transport
blood coagulation
negative regulation of endopeptidase activity
peptidyl-glutamic acid carboxylation
regulation of complement activation
response to lipopolysaccharide
fibrinolysis
positive regulation of phagocytosis
leukocyte migration
hemostasis
negative regulation of coagulation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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