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Proteintech
PSAP Polyclonal Antibody, CoraLite® Plus 488
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
CL488-10801
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PSAP fusion protein Ag1194
Conjugate
CoraLite® Plus 488
CoraLite® Plus 488
CoraLite® Plus 488
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MYALFLLAS LLGAALAGPV LGLKECTRGS AVWCQNVKTA SDCGAVKHCL QTVWNKPTVK SLPCDICKDV VTAAGDMLKD NATEEEILVY LEKTCDWLPK PNMSASCKEI VDSYLPVILD IIKGEMSRPG EVCSALNLCE SLQKHLAELN HQKQLESNKI PELDMTEVVA PFMANIPLLL YPQDGPRSKP QPKDNGDVCQ DCIQMVTDIQ TAVRTNSTFV QALVEHVKEE CDRLGPGMAD ICKNYISQYS EIAIQMMMHM QPKEICALVG FCDEVKEMPM QTLVPAKVAS KNVIPALELV EPIKKHEVPA KSDVYCEVCE F
Target Information
PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: co-beta glucosidase precursor; precursor of saposins; proactivator polypeptide; prosaposin; PSAP; saposin-A; saposin-B; saposin-C; saposin-D; sphingolipid activator protein-1; sphingolipid activator protein-2; unnamed protein product
Gene Aliases: GLBA; PARK24; PSAPD; SAP1; SAP2
UniProt ID: (Human) P07602
Entrez Gene ID: (Human) 5660
protease binding
protein binding
phospholipid binding
lipid binding
sphingolipid activator protein activity
identical protein binding
protein homodimerization activity
scaffold protein binding
ganglioside GM1 binding
ganglioside GM2 binding
ganglioside GM3 binding
ganglioside GT1b binding
ganglioside GP1c binding
lipid chaperone activity
lipid metabolic process
sphingolipid metabolic process
sphingomyelin catabolic process
lysosomal transport
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
gene expression
regulation of autophagy
regulation of lipid metabolic process
sphingolipid catabolic process
prostate gland growth
epithelial cell differentiation involved in prostate gland development
ganglioside GM1 transport to membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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