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Invitrogen
PSCA Polyclonal Antibody
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Product Details
PA5-95237
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human PSCA recombinant protein (Position: L21-S95).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Human PSCA shares 66% amino acid (aa) sequence identity with mouse PSCA.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Stomach Tissue, Mouse Stomach Tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in approximately40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: caldesmon; CDM; GPI-anchored cell surface protein; H-CAD; HCAD; L-CAD; LCAD; NAG22; Prostate stem cell antigen; UNQ206
Gene Aliases: 2210408B04Rik; lncPSCA; PRO232; PSCA; UNQ206/PRO232
UniProt ID: (Human) O43653, (Mouse) P57096
Entrez Gene ID: (Human) 8000, (Mouse) 72373
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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