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Product Details
PA5-144808
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 223-263. Recombinant protein control fragment (Product #RP-109735).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3092341
Product Specific Information
Immunogen sequence: RNLYAMHRRL QRHPRSCTRD CAEPRADGRE ASPQPLEELD H^M
^M
Antigen sequence identity: Mouse 54%; Rat 63%
Target Information
The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dp receptor; MGC49004; PGD receptor; PGD2 receptor; Prostaglandin D2 receptor; prostaglandin D2 receptor (DP); Prostanoid DP receptor
Gene Aliases: AS1; ASRT1; DP; DP1; PTGDR; PTGDR1
UniProt ID: (Human) Q13258
Entrez Gene ID: (Human) 5729
inflammatory response
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
male sex determination
sleep
positive regulation of vasodilation
adenosine metabolic process
cellular response to prostaglandin D stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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