Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Elephant, Panda, Bat, Dog, Rabbit, Horse, Turkey, Chicken, Platypus (100%).
The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: PGF receptor; PGF2 alpha receptor; PGF2-alpha receptor; Prostaglandin F receptor; Prostaglandin F receptor (FP); prostaglandin F2 alpha receptor; Prostaglandin F2-alpha receptor; prostaglandin receptor (2-alpha); Prostanoid FP receptor; PTGFR
Gene Aliases: FP; PTGFR
UniProt ID: (Human) P43088
Entrez Gene ID: (Human) 5737