Recommended positive controls: A549, H1299, HCT116.
Predicted reactivity: Human (99%), Mouse (91%), Rhesus Monkey (97%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CCK4 may function as a cell adhesion molecule. Although it belongs to the insulin receptor subfamily of the Tyr protein kinases, it likely lacks the catalytic activity of a tyrosine kinase. It may be connected to the pathophysiology of colon carcinomas and/or may represent a tumor progression marker. This Type I membrane protein is highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes, but weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle, and not in colon. It is also expressed in erythroleukemia cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CCK-4; Colon carcinoma kinase 4; Inactive tyrosine-protein kinase 7; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; PTK7 protein tyrosine kinase 7; Tyrosine-protein kinase-like 7
Gene Aliases: CCK-4; CCK4; PTK7
UniProt ID: (Human) Q13308
Entrez Gene ID: (Human) 5754