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Invitrogen
PTPRD Polyclonal Antibody
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Product Details
PA5-34392
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
An 18 amino acid synthetic peptide near the amino terminus of human PTPRD
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is Hela cell lysate.
PA5-34392 can be used with blocking peptide PEP-1435.
Target Information
PTPRD is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: protein tyrosine phosphatase, receptor type, delta polypeptide; Protein-tyrosine phosphatase delta; rceptor-type tyrosine-protein phosphatase delta; Receptor-type tyrosine-protein phosphatase delta; unnamed protein product
Gene Aliases: HPTP; HPTPD; HPTPDELTA; PTPD; PTPRD; R-PTP-delta; RPTPDELTA
UniProt ID: (Human) P23468
Entrez Gene ID: (Human) 5789
phosphate-containing compound metabolic process
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
signal transduction
transmembrane receptor protein tyrosine phosphatase signaling pathway
nervous system development
neuron differentiation
negative regulation of JAK-STAT cascade
positive regulation of dendrite morphogenesis
regulation of immune response
modulation of synaptic transmission
positive regulation of synapse assembly
positive regulation of dendritic spine morphogenesis
presynaptic membrane assembly
presynapse assembly
regulation of postsynaptic density assembly
trans-synaptic signaling
trans-synaptic signaling by trans-synaptic complex
synaptic membrane adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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