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Product Details
BS-5695R
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLH conjugated synthetic phosphopeptide derived from human rab effector Noc2 isoform 2 around the phosphorylation site of Ser232 [HL (p-S)GC]. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS with 50% glycerol, 1% BSA |
Contains |
0.09% sodium azide |
Storage conditions |
-20°C |
Target Information
The protein encoded by this gene plays a direct regulatory role in calcium-ion-dependent exocytosis in both endocrine and exocrine cells and plays a key role in insulin secretion by pancreatic cells. This gene is likely a tumor suppressor. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: No C2 domains protein; Rab effector Noc2; Rabphilin-3A-like protein
Gene Aliases: NOC2; RPH3AL
UniProt ID: (Human) Q9UNE2
Entrez Gene ID: (Human) 9501
intracellular protein transport
exocytosis
vesicle fusion
regulation of calcium ion-dependent exocytosis
response to drug
glucose homeostasis
negative regulation of G-protein coupled receptor protein signaling pathway
calcium ion-regulated exocytosis of neurotransmitter
positive regulation of protein secretion
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