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Invitrogen
Phospho-Raptor (Ser863) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-Raptor (Ser863) Antibody (PA5-64849) in WB
Western Blot analysis of Phospho-Raptor (Ser863) was performed using lysates of (1) MCF-7 cell and (2) HepG2 cell. The membrane was probed with Phospho-Raptor (Ser863) Polyclonal Antibody (Product # PA5-64849) using a dilution of 1:1,000.
Product Details
PA5-64849
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human Raptor (Phospho-Ser863)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Phospho-Raptor (Ser863) Polyclonal Antibody detects endogenous levels of Raptor only when phosphorylated at Ser863.
Target Information
Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of raptor to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro. It enhances the mTOR kinase activity toward p70alpha. It is also an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: p150 target of rapamycin (TOR)-scaffold protein; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; Raptor; regulatory associated protein of MTOR, complex 1; Regulatory-associated protein of mTOR
Gene Aliases: 4932417H02Rik; KIAA1303; KOG1; Mip1; mKIAA1303; Rap; RAPTOR; RGD1311784; RPTOR
UniProt ID: (Human) Q8N122
Entrez Gene ID: (Human) 57521, (Mouse) 74370, (Rat) 287871
RNA polymerase III type 1 promoter DNA binding
RNA polymerase III type 2 promoter DNA binding
RNA polymerase III type 3 promoter DNA binding
TFIIIC-class transcription factor binding
protein binding
protein kinase binding
protein kinase activator activity
protein binding, bridging
protein complex binding
14-3-3 protein binding
positive regulation of endothelial cell proliferation
regulation of cell size
cell growth
cellular response to nutrient levels
TOR signaling
positive regulation of TOR signaling
regulation of phosphorylation
positive regulation of transcription from RNA polymerase III promoter
cellular response to amino acid stimulus
positive regulation of protein serine/threonine kinase activity
cell cycle arrest
macroautophagy
activation of protein kinase activity
regulation of cellular response to heat
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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