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|Tested species reactivity||Human , Mouse , Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from human Src around the phosphorylation site of Serine 75|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Concentration is lot-specific and will vary from 0.5-0.6 mg/ml
Src is a non-receptor tyrosine kinase that associates with the cytoplasmic region of various cell surface receptors to facilitate signal transduction. Src is involved in in cytoskeletal organization, cell cycle regulation, and apoptosis. In humans, the gene encoding Src is present on chromosome 20.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
c-Src; EC 220.127.116.11p60-Srcc-Srcpp60c-src; neuronal proto-oncogene tyrosine-protein kinase Src; p60-Src; pp60c-src; proto-oncogene c-Src; proto-oncogene tyrosine-protein kinase Src; protooncogene SRC, Rous sarcoma; Rous sarcoma oncogene; tyrosine kinase pp60c-src; tyrosine protein kinase c-src; tyrosine protein kinase pp60-c-src; tyrosine-protein kinase SRC-1; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
ASV; AW259666; c-SRC; p60-Src; pp60c-src; RP5-823N20.1; SRC1
Carbohydrate metabolism Protein metabolism and modification Protein modification Protein phosphorylation Signal transduction Intracellular signaling cascade Transport Carbohydrate transport Immunity and defense Oncogenesis Oncogene Developmental processes Gametogenesis Oogenesis Embryogenesis Ectoderm development Neurogenesis Mesoderm development Cell cycle Cell cycle control Cell proliferation and differentiation