This antibody is predicted to react with mouse based on sequence homology.
This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.
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Protein Aliases: PIR; Pirin; pirin (iron-binding nuclear protein); Probable quercetin 2,3-dioxygenase PIR; Probable quercetinase
Gene Aliases: PIR
UniProt ID: (Human) O00625
Entrez Gene ID: (Human) 8544