|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 316 and 597 of Plasma Kallikrein 1B (Uniprot ID#P03952)|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:5000-1:20,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-34876 targets Plasma Kallikrein in WB applications and shows reactivity with Human and Mouse samples.
The PA5-34876 immunogen is recombinant fragment corresponding to a region within amino acids 316 and 597 of Plasma Kallikrein 1B (Uniprot ID#P03952).
The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.