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Product Details
14868-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Plasmolipin Fusion Protein Ag6425 (1-182 aa encoded by BC002760)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAEFPSKVS TRTSSPAQGA EASVSALRPD LGFVRSRLGA LMLLQLVLGL LVWALIADTP YHLYPAYGWV MFVAVFLWLV TIVLFNLYLF QLHMKLYMVP WPLVLMIFNI SATVLYITAF IACSAAVDLT SLRGTRPYNQ RAAASFFACL VMIAYGVSAF FSYQAWRGVG SNAATSQMAG GYA (1-182 aa encoded by BC002760)
Target Information
Plasmolipin is an 18 kDa membrane-bound proteolipid that belongs to the tetraspan (4TM) family, a rapidly growing group of myelin-associated proteins. Many of these proteins could be linked to human hereditary demyelinating neuropathies. Studies indicate that plasmolipin is a component of the cytoskeletal structure and has been localized to the apical surface of tubular epithelial cells. It has been shown that, upon addition to lipid bilayers, plasmolipin induces formation of ion channels that are both voltage-dependent and potassium-specific. Plasmolipin was originally isolated from kidney tissue. Subsequently, it has been shown to be widely expressed, not only being present in kidney, but also in the nervous system, thymus, testis, lung, and thyroid gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Plasma membrane proteolipid; plasma membrane proteolipid (plasmolipin); Plasmolipin; transmembrane 4 superfamily member 11; transmembrane 4 superfamily member 11 (plasmolipin)
Gene Aliases: 0610010I06Rik; AV001002; Plapi; PLLP; PMLP; TM4SF11
UniProt ID: (Human) Q9Y342, (Rat) P47987, (Mouse) Q9DCU2
Entrez Gene ID: (Human) 51090, (Rat) 64364, (Mouse) 67801
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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