Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-74140 detects Platelet Factor 4 from human samples.
PA1-74140 has been successfully used in ELISA and immunoelectrophoresis applications.
The PA1-74140 immunogen is Platelet factor 4 from human platelets.
Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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