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Invitrogen
Properdin Polyclonal Antibody
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Product Details
PA5-109520
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein (or fragment)
Conjugate
Form
Liquid
Concentration
0.76 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: CPTHGAWATW GPWTPCSASC HGGPHEPKET RSRKCSAPEP SQKPPGKPCP GLAYEQRRCT GLPPCPVAGG WGPWGPVSPC PVTCGLGQTM EQRTCNHPVP QHGGPFCAGD ATRTHICNTA VPCPVDGEWD SWGEWSPCIR RNMKSISCQE IPGQQSRGRT CRGRKFDGHR CAGQQQDIRH CYSIQHCPLK GSWSEWSTWG LCMPPCGPNP TRARQRLCTP LLPKYPPTVS MVEGQGEKNV TFWGRPLPRC EELQGQKLVV EEKRPCLHVP ACKDPEEEEL
Target Information
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bf; C3 Proaccelerator; C3/C5 convertase; cfb; Complement factor P; GBG; H2-Bf; PBF2; Properdin; properdin factor, complement; Properdin P factor, complement
Gene Aliases: BCFG; BFD; CFP; PFC; PFD; PROPERDIN
UniProt ID: (Human) P27918, (Mouse) P11680
Entrez Gene ID: (Human) 5199, (Rat) 299314, (Mouse) 18636
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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