|Tested species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Human Protein Z.|
|Purification||Ammonium sulfate precipitation, Ion-exchange chromatography|
|Storage buffer||0.01M HEPES, pH 7.4, with 0.15M NaCl, 50% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||5-10 µg/mL|
|Western Blot (WB)||25 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-43060 detects Protein Z in human samples.
PA1-43060 has successfully been used in Western blot and ELISA applications.
PA1-43060 was derived from human protein Z.
Protein Z is a 62-kD vitamin K-dependent plasma protein and Protein Z promotes the association of thrombin with phospholipid surfaces. Human Protein Z is synthesized with a prepro-leader sequence of 40 amino acids. The mature protein is contains 360 residues including a Gla domain of 13 carboxyglutamic acid residues, 2 epidermal growth factor domains, and a carboxyl terminal region that is highly homologous to the catalytic domain of serine proteases. Its structure is similar to that of factors VII, IX, and X, and protein C.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.