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Positive Control: 293T, A431, human plasma, mouse plasma, rat plasma
Predicted Reactivity: Rhesus Monkey (96%), Bovine (80%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Prothrombin or Coagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: coagulation factor 2; Coagulation factor II; coagulation factor II (thrombin); prepro-coagulation factor II; Prothrombin; prothrombin B-chain; serine protease; thrombin
Gene Aliases: Cf-2; Cf2; F2; FII; PT; RPRGL2; THPH1
UniProt ID: (Mouse) P19221, (Human) P00734
Entrez Gene ID: (Mouse) 14061, (Rat) 29251, (Human) 2147
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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