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Proteintech
QPRT Polyclonal Antibody
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Product Details
25174-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
QPRT Fusion Protein Ag17680 (1-297 aa encoded by BC018910)
Conjugate
Form
Liquid
Concentration
0.41 mg/mL
Amount
61.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDAEGLALL LPPVTLAALV DSWLREDCPG LNYAALVSGA GPSQAALWAK SPGVLAGQPF FDAIFTQLNC QVSWFLPEGS KLVPVARVAE VRGPAHCLLL GERVALNTLA RCSGIASAAA AAVEAARGAG WTGHVAGTRK TTPGFRLVEK YGLLVGGAAS HRYDLGGLVM VKDNHVVAAG GVEKAVRAAR QAADFALKVE VECSSLQEAV QAAEAGADLV LLDNFKPEEL HPTATVLKAQ FPSVAVEASG GITLDNLPQF CGPHIDVISM GMLTQAAPAL DFSLKLFAKE VAPVPKIH (1-297 aa encoded by BC018910)
Target Information
QPRT gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein Li 90n; nicotinate-nucleotide pyrophosphorylase (carboxylating); Nicotinate-nucleotide pyrophosphorylase [carboxylating]; QAPRTase; Quinolinate phosphoribosyltransferase [decarboxylating]; unnamed protein product
Gene Aliases: HEL-S-90n; QPRT; QPRTase
UniProt ID: (Human) Q15274
Entrez Gene ID: (Human) 23475
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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