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Invitrogen
QSOX1 Polyclonal Antibody
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FIGURE: 1 / 1
QSOX1 Antibody (PA5-120881) in WB
Western blot analysis of QSOX1 in extracts of various cell lines. Samples were incubated with QSOX1 Polyclonal antibody (Product # PA5-120881) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-120881
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human QSOX1 (NP_001004128.1).
Conjugate
Form
Liquid
Concentration
2.671 mg/mL
Amount
267.1 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: NCI-H460, U-251MG, Mouse heart. The target is usually found in the following locations: Golgi apparatus membrane, Secreted, Single-pass membrane protein, extracellular space.
Immunogen sequence: MRRCNSGSGP PPSLLLLLLW LLAVPGANAA PRSALYSPSD PLTLLQADTV RGAVLGSRSA WAVEFFASWC GHCIAFAPTW KALAEDVKAW RPALYLAALD CAEETNSAVC RDFNIPGFPT VRFFKAFTKN GSGAVFPVAG ADVQTLRERL IDALESHHDT WPPACPPLEP AKLEEIDGFF ARNNEEYLAL IFEKGGSYLG REVALDLSQH KGVAVRRVLN TEANVVRKFG VTDFPSCYLL FRNGSVSRVP VLMESRSFYT AYLQRLSGLT REAAQTTVAP TTANKIAPTV WKLADRSKIY MADLESALHY ILRIEVGRFP VLEGQRLVAL
Target Information
The QSOX1 gene, also known as Quiescin Q6, is a fusion of two ancient genes: thioredoxin and ERV1. Its expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. The QSOX1 protein oxidizes sulfhydryl groups to form disulfide bonds in proteins. QSOX1 expression is induced by hypoxia and appears to protect cells against oxidative stress-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternatively spliced; probable sulfhydryl oxidase; hQSOX; mSOx; Quiescin Q6; quiescin Q6 sulfhydryl oxidase 1; RP11-502H18.3; Skin sulfhydryl oxidase; Sulfhydryl oxidase 1; testis tissue sperm-binding protein Li 62n; thiol oxidase 1; unnamed protein product
Gene Aliases: 1300003H02Rik; Q6; QSCN6; QSOX; QSOX1; SOx; UNQ2520/PRO6013
UniProt ID: (Human) O00391, (Mouse) Q8BND5
Entrez Gene ID: (Human) 5768, (Mouse) 104009
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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