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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 142 and 415 of Human QTRTD1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-32075 targets QTRTD1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-32075 immunogen is recombinant fragment corresponding to a region within amino acids 142 and 415 of Human QTRTD1.
Interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
queuine tRNA-ribosyltransferase domain containing 1; queuine tRNA-ribosyltransferase domain-containing protein 1; queuine tRNA-ribosyltransferase subunit QTRTD1