Proteintech

RAB3C Polyclonal Antibody

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RAB3C Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human ovary tumor using 10788-1-AP (RAB3C antibody) at dilution of 1:100 (under 10x lens).

RAB3C Antibody in Western Blot (WB) — Mouse brain tissue were subjected to SDS PAGE followed by western blot with 10788-1-AP (RAB3C antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

RAB3C Antibody in Immunoprecipitation (IP) — IP result of anti-RAB3C (IP:10788-1-AP, 4ug; Detection:10788-1-AP 1:300) with mouse brain tissue lysate 4000ug.

Product Details

10788-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	View 1 publication 1 publication
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	-	View 2 publications 2 publications
Immunoprecipitation (IP)	0.5-4.0 µg	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	RAB3C Fusion Protein Ag1241 (1-227 aa encoded by BC013033) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.15 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MRHEAPMQM ASAQDARYGQ KDSSDQNFDY MFKLLIIGNS SVGKTSFLFR YADDSFTSAF VSTVGIDFKV KTVFKNEKRI KLQIWDTAGQ ERYRTITTAY YRGAMGFILM YDITNEESFN AVQDWSTQIK TYSWDNAQVI LVGNKCDMED ERVISTERGQ HLGEQLGFEF FETSAKDNIN VKQTFERLVD IICDKMSESL ETDPAITAAK QNTRLKETPP PPQPNCAC (1-227 aa encoded by BC013033)

Target Information

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 3C is found in brain, adrenal gland, and pituitary.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.