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Product Details
PA5-96368
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunocytochemistry (ICC/IF) |
1:50 - 1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RAB6A. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.23 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2808170 |
Product Specific Information
Immunogen sequence: MSTGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF LSKTMYLEDR TIRLQLWDTA GQERFRSLIP SYIRDSAAAV VVYDITNVNS FQQTTKWIDD VRTERGSDVI IMLVGNKTDL ADKRQVSIEE GERKAKELNV MFIETSAKAG YNVKQLFRRV AAALPGMEST QDRSREDMID IKLEKPQEQP; Positive Samples: BT-474, OVCAR3, SW480, HT-29, 293T, SH-SY5Y, Mouse brain, Mouse lung, Mouse intestine; Cellular Location: Golgi apparatus, Golgi apparatus membrane, Lipid-anchor
Target Information
Rab proteins are also an integral part of endocytic pathways. Rab 6A is a ubiquitously expressed member of the Rab family of proteins and localizes to the Golgi membrane where it regulates retrograde transport from the late endosomes via the Golgi to endoplasmic reticulum (ER) pathway. Three isoforms exist due to alternative splicing events, namely the ubiquitously expressed isoforms Rab 6A' and Rab 6A, and the brain-specific isoform Rab 6B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Rab GTPase; Rab-6; RAB6, member RAS oncogene family; Ras-related protein Rab-6A
Gene Aliases: 2610028L11Rik; AA419671; MNCb-1660; RAB6; RAB6A
UniProt ID: (Human) P20340, (Mouse) P35279
Entrez Gene ID: (Human) 5870, (Mouse) 19346
protein targeting to Golgi
retrograde vesicle-mediated transport, Golgi to ER
small GTPase mediated signal transduction
viral process
peptidyl-cysteine methylation
antigen processing and presentation
protein localization to Golgi apparatus
early endosome to Golgi transport
minus-end-directed organelle transport along microtubule
transport
intracellular protein transport
intra-Golgi vesicle-mediated transport
protein transport
vesicle-mediated transport
Rab protein signal transduction
positive regulation of ATPase activity
retrograde transport, endosome to Golgi
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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