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          • Primary Antibodies ›
          • RAC1/RAC2/RAC3 Antibodies

          Invitrogen

          RAC1/RAC2/RAC3 Polyclonal Antibody

          Advanced Verification
          View all (6) RAC1/RAC2/RAC3 antibodies

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          Cite RAC1/RAC2/RAC3 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (7)
          • Advanced Verification (1)
          RAC1/RAC2/RAC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          RAC1/RAC2/RAC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          RAC1/RAC2/RAC3 Antibody (PA5-61600) in IHC (P)

          Immunohistochemical analysis of RAC1/RAC2/RAC3 in human colon using RAC1/RAC2/RAC3 Polyclonal Antibody (Product # PA5-61600) shows weak to moderate membranous/ cytoplasmic positivity in glandular cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          RAC1/RAC2/RAC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RAC1/RAC2/RAC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RAC1/RAC2/RAC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RAC1/RAC2/RAC3 Antibody in Immunohistochemistry (IHC)
          RAC1/RAC2/RAC3 Antibody in Western Blot (WB)
          RAC1/RAC2/RAC3 Antibody in Western Blot (WB)
          RAC1/RAC2/RAC3 Antibody in Western Blot (WB)
          RAC1/RAC2/RAC3 Antibody

          Product Details

          PA5-61600

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human RAC1/RAC2/RAC3

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Amount

          10 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2646272

          Product Specific Information

          Immunogen sequence: TKLDLRDDKD TIERLRDKKL APITYPQGLA MAREI

          Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

          Target Information

          The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Cell migration-inducing gene 5 protein; GX; p21-Rac1; p21-Rac2; p21-Rac3; Rac1ins; RAC2; ras-like protein; Ras-like protein TC25; ras-related C3 botulinum toxin substrate; Ras-related C3 botulinum toxin substrate 1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); Ras-related C3 botulinum toxin substrate 2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); Ras-related C3 botulinum toxin substrate 3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3); Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); rho family, small GTP binding protein Rac3; Small G protein; unnamed protein product

          View more View less

          Gene Aliases: EN-7; Gx; HSPC022; IMD73A; IMD73B; IMD73C; MIG5; MRD48; p21-Rac1; p21-Rac2; Rac-1; RAC1; RAC2; RAC3; TC-25; TC25

          View more View less

          UniProt ID: (Human) P63000, (Human) P15153, (Human) P60763

          View more View less

          Entrez Gene ID: (Human) 5879, (Human) 5880, (Human) 5881

          View more View less

          Function(s)
          nucleotide binding GTPase activity obsolete small monomeric GTPase activity protein binding GTP binding hydrolase activity enzyme binding protein kinase binding GTP-dependent protein binding thioesterase binding macromolecular complex binding Rho GDP-dissociation inhibitor binding protein kinase regulator activity calcium-dependent protein binding
          Process(es)
          actin filament organization establishment or maintenance of cell polarity small GTPase mediated signal transduction motor neuron axon guidance regulation of cell shape regulation of cell-substrate adhesion regulation of neuron maturation Wnt signaling pathway Rac protein signal transduction cerebral cortex GABAergic interneuron development regulation of cell morphogenesis cell projection assembly actin cytoskeleton organization cortical cytoskeleton organization neuron projection development regulation of actin cytoskeleton organization positive regulation of cell adhesion mediated by integrin intracellular signal transduction respiratory burst homeostasis of number of cells within a tissue neuromuscular process controlling balance neuromuscular process synaptic transmission, GABAergic cell chemotaxis postsynaptic actin cytoskeleton organization regulation of postsynapse assembly positive regulation of substrate adhesion-dependent cell spreading regulation of neutrophil migration chemotaxis signal transduction G-protein coupled receptor signaling pathway cell proliferation regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly regulation of T cell proliferation superoxide anion generation erythrocyte enucleation regulation of mast cell degranulation bone resorption regulation of respiratory burst regulation of mast cell chemotaxis mast cell proliferation positive regulation of mast cell proliferation lymphocyte aggregation positive regulation of neutrophil chemotaxis positive regulation of protein targeting to mitochondrion neuron migration positive regulation of protein phosphorylation auditory receptor cell morphogenesis sphingosine-1-phosphate signaling pathway epithelial cell morphogenesis endocytosis phagocytosis, engulfment inflammatory response hyperosmotic response cytoskeleton organization cell adhesion cell-matrix adhesion enzyme linked receptor protein signaling pathway axon guidance response to wounding anatomical structure morphogenesis regulation of lamellipodium assembly positive regulation of endothelial cell migration regulation of fibroblast migration negative regulation of fibroblast migration positive regulation of cell-substrate adhesion dendrite development cell migration cerebral cortex radially oriented cell migration embryonic olfactory bulb interneuron precursor migration lamellipodium assembly actin filament polymerization regulation of cell migration positive regulation of actin filament polymerization forebrain development positive regulation of microtubule polymerization ruffle organization response to lipopolysaccharide negative regulation of interleukin-23 production substrate adhesion-dependent cell spreading positive regulation of Rho protein signal transduction non-canonical Wnt signaling pathway positive regulation of insulin secretion involved in cellular response to glucose stimulus engulfment of apoptotic cell cell-cell junction organization regulation of nitric oxide biosynthetic process regulation of JAK-STAT cascade hepatocyte growth factor receptor signaling pathway regulation of neuronal synaptic plasticity negative regulation of receptor-mediated endocytosis anatomical structure arrangement neuron projection morphogenesis dendrite morphogenesis cell motility regulation of stress fiber assembly positive regulation of stress fiber assembly localization within membrane positive regulation of focal adhesion assembly positive regulation of protein kinase B signaling Wnt signaling pathway, planar cell polarity pathway positive regulation of dendritic spine development regulation of cell adhesion involved in heart morphogenesis regulation of ERK5 cascade semaphorin-plexin signaling pathway dopaminergic neuron differentiation protein localization to plasma membrane angiotensin-activated signaling pathway involved in heart process cochlea morphogenesis ruffle assembly positive regulation of ruffle assembly regulation of synaptic vesicle endocytosis positive regulation of bicellular tight junction assembly positive regulation of skeletal muscle acetylcholine-gated channel clustering interneuron migration midbrain dopaminergic neuron differentiation positive regulation of ovarian follicle development regulation of neuron migration
          It has to be done as per old AB suggested Products section.

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