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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • RAC1/RAC2/RAC3/CDC42 Antibodies

          Invitrogen

          RAC1/RAC2/RAC3/CDC42 Polyclonal Antibody

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          Cite RAC1/RAC2/RAC3/CDC42 Polyclonal Antibody

          • Antibody Testing Data (1)
          RAC1/RAC2/RAC3/CDC42 Antibody in Western Blot (WB)
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          RAC1/RAC2/RAC3/CDC42 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          RAC1/RAC2/RAC3/CDC42 Antibody (PA5-99700) in WB

          Western blot analysis of RAC1/RAC2/RAC3/CDC42 in HepG2 cell lysate. Samples were incubated with RAC1/RAC2/RAC3/CDC42 polyclonal antibody (Product # PA5-99700). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          RAC1/RAC2/RAC3/CDC42 Antibody in Western Blot (WB)
          RAC1/RAC2/RAC3/CDC42 Polyclonal Antibody

          Product Details

          PA5-99700

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human RAC1(Accession P63000), corresponding to amino acid residues M45-A95.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2818633

          Product Specific Information

          Antibody detects endogenous levels of total Rac1/2/3.

          Target Information

          The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Cell division control protein 42 homolog; cell division cycle 42 (GTP binding protein); cell division cycle 42 homolog; Cell migration-inducing gene 5 protein; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); EN-7 protein; G25K GTP-binding protein; growth-regulating protein; GTP binding protein, 25kDa; GX; p21-Rac1; p21-Rac2; p21-Rac3; Protein EN-7; Ras-like protein TC25; RAS-related C3 botulinum substrate 2; Ras-related C3 botulinum toxin substrate 1; ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1); Ras-related C3 botulinum toxin substrate 2; Ras-related C3 botulinum toxin substrate 3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3); Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); rho family, small GTP binding protein Rac1; rho family, small GTP binding protein Rac3; Small G protein; small GTP binding protein CDC42

          View more View less

          Gene Aliases: AI323801; AI452260; AI747189; AL023026; AU018915; CDC42; CDC42Hs; D5Ertd559e; EN-7; G25K; Gx; HSPC022; MIG5; p21-Rac1; p21-Rac2; Rac; Rac-1; RAC1; Rac1B; RAC2; RAC3; TC-25; TC25; TKS

          View more View less

          UniProt ID: (Human) P60953, (Rat) Q8CFN2, (Mouse) P60766, (Human) P63000, (Human) P15153, (Human) P60763, (Mouse) P63001, (Rat) Q6RUV5, (Mouse) Q05144, (Mouse) P60764

          View more View less

          Entrez Gene ID: (Human) 998, (Rat) 64465, (Mouse) 12540, (Human) 5879, (Human) 5880, (Human) 5881, (Mouse) 19353, (Rat) 363875, (Rat) 366957, (Mouse) 19354, (Mouse) 170758, (Rat) 688319

          View more View less

          Function(s)
          GTPase activity protein binding GTP binding protein kinase binding GTP-dependent protein binding mitogen-activated protein kinase kinase kinase binding thioesterase binding apolipoprotein A-I receptor binding identical protein binding Rho GDP-dissociation inhibitor binding ubiquitin protein ligase activity nucleotide binding Rab GTPase binding enzyme binding histone deacetylase binding protein kinase regulator activity calcium-dependent protein binding small GTPase immunoglobulin
          Process(es)
          sprouting angiogenesis cardiac conduction system development keratinocyte development Golgi organization regulation of mitotic nuclear division nuclear migration establishment or maintenance of cell polarity small GTPase mediated signal transduction blood coagulation positive regulation of gene expression negative regulation of gene expression protein ubiquitination substantia nigra development actin cytoskeleton organization macrophage differentiation positive regulation of cell growth hair follicle morphogenesis positive regulation of pseudopodium assembly T cell costimulation negative regulation of protein complex assembly keratinization regulation of protein stability positive regulation of cytokinesis positive regulation of peptidyl-serine phosphorylation adherens junction organization cellular protein localization establishment or maintenance of apical/basal cell polarity multicellular organism growth dendritic cell migration Fc-gamma receptor signaling pathway involved in phagocytosis negative regulation of epidermal growth factor receptor signaling pathway regulation of protein catabolic process regulation of protein heterodimerization activity positive regulation of neuron apoptotic process positive regulation of phosphatidylinositol 3-kinase activity positive regulation of DNA replication regulation of protein kinase activity positive regulation of JNK cascade filopodium assembly vascular endothelial growth factor receptor signaling pathway ephrin receptor signaling pathway neuron fate determination actin filament bundle assembly regulation of small GTPase mediated signal transduction positive regulation of muscle cell differentiation regulation of filopodium assembly establishment of Golgi localization positive regulation of synapse structural plasticity regulation of attachment of spindle microtubules to kinetochore heart contraction canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway positive regulation of epithelial cell proliferation involved in lung morphogenesis submandibular salivary gland formation epithelial-mesenchymal cell signaling hair follicle placode formation positive regulation of hair follicle cell proliferation organelle transport along microtubule actin filament branching epithelial cell-cell adhesion positive regulation of intracellular protein transport positive regulation of substrate adhesion-dependent cell spreading positive regulation of protein phosphorylation endocytosis actin filament organization metabolic process response to glucose single organismal cell-cell adhesion regulation of exocytosis establishment of cell polarity positive regulation of catalytic activity positive regulation of MAPK cascade epidermis morphogenesis regulation of protein metabolic process nucleus localization Rho protein signal transduction nervous system development endosomal transport cell differentiation auditory receptor cell morphogenesis mast cell chemotaxis epithelial cell morphogenesis movement of cell or subcellular component inflammatory response hyperosmotic response cell adhesion cell-matrix adhesion G-protein coupled receptor signaling pathway axon guidance cell proliferation regulation of cell size response to wounding anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly regulation of fibroblast migration positive regulation of cell-substrate adhesion regulation of neuron maturation cerebral cortex radially oriented cell migration embryonic olfactory bulb interneuron precursor migration cerebral cortex GABAergic interneuron development lamellipodium assembly actin filament polymerization platelet activation regulation of cell migration positive regulation of actin filament polymerization ruffle organization negative regulation of interleukin-23 production substrate adhesion-dependent cell spreading positive regulation of Rho protein signal transduction intracellular signal transduction Fc-epsilon receptor signaling pathway positive regulation of apoptotic process engulfment of apoptotic cell cell-cell junction organization bone resorption negative regulation of receptor-mediated endocytosis anatomical structure arrangement dendrite morphogenesis cell motility homeostasis of number of cells within a tissue regulation of defense response to virus by virus positive regulation of stress fiber assembly localization within membrane positive regulation of focal adhesion assembly synaptic transmission, GABAergic regulation of respiratory burst cellular response to mechanical stimulus semaphorin-plexin signaling pathway dopaminergic neuron differentiation protein localization to plasma membrane positive regulation of neutrophil chemotaxis cochlea morphogenesis ruffle assembly chemotaxis signal transduction positive regulation of cell proliferation regulation of cell-substrate adhesion cell projection assembly regulation of T cell proliferation regulation of mast cell degranulation regulation of mast cell chemotaxis lymphocyte aggregation regulation of neutrophil migration positive regulation of protein targeting to mitochondrion neuron projection development positive regulation of cell adhesion mediated by integrin neuromuscular process controlling balance phagocytosis, engulfment cytoskeleton organization dendrite development cell migration regulation of cell morphogenesis Rac protein signal transduction neuromuscular process
          It has to be done as per old AB suggested Products section.
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