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          • Primary Antibodies ›
          • RAC1/RAC2/RAC3/CDC42 Antibodies

          Invitrogen

          RAC1/RAC2/RAC3/CDC42 Polyclonal Antibody

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          Cite RAC1/RAC2/RAC3/CDC42 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          RAC1/RAC2/RAC3/CDC42 Antibody in Western Blot (WB)
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          RAC1/RAC2/RAC3/CDC42 Antibody in Western Blot (WB)
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          RAC1/RAC2/RAC3/CDC42 Antibody (PA5-99700) in WB

          Western blot analysis of RAC1/RAC2/RAC3/CDC42 in HepG2 cell lysate. Samples were incubated with RAC1/RAC2/RAC3/CDC42 polyclonal antibody (Product # PA5-99700). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          RAC1/RAC2/RAC3/CDC42 Antibody in Western Blot (WB)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          RAC1/RAC2/RAC3/CDC42 Polyclonal Antibody

          Product Details

          PA5-99700

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human RAC1(Accession P63000), corresponding to amino acid residues M45-A95.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2818633

          Product Specific Information

          Antibody detects endogenous levels of total Rac1/2/3.

          Target Information

          The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Cdc42; CDC42Mm; cell division cycle 42 (GTP binding protein); cell division cycle 42 homolog; cell migration-inducing gene 5 protein; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); EN-7 protein; G25K GTP-binding protein; growth-regulating protein; GTP binding protein, 25kDa; GTP-binding protein; GTP-binding protein G25K; p21-Rac1; p21-Rac2; p21-Rac3; protein EN-7; Rac1ins; RAC2; ras-like protein; ras-like protein TC25; RAS-related C3 botulinum substrate 1; RAS-related C3 botulinum substrate 2; RAS-related C3 botulinum substrate 3; ras-related C3 botulinum toxin substrate; ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3); Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); rho family, small GTP binding protein Rac1; rho family, small GTP binding protein Rac3; small G protein; small GTP binding protein; small GTP binding protein CDC42; small GTP binding protein; GTPase; small GTP binding protein; Rac1; Rho-related protein; unnamed protein product

          View more View less

          Gene Aliases: CDC42Hs; D5Ertd559e; EN-7; G25K; Gx; HSPC022; IMD73A; IMD73B; IMD73C; MIG5; MRD48; p21-Rac1; p21-Rac2; Rac-1; Rac1B; TC-25; TKS

          View more View less

          UniProt ID: (Human) P60953, (Mouse) P60766, (Rat) Q8CFN2, (Human) P63000, (Human) P15153, (Human) P60763, (Mouse) P63001, (Rat) Q6RUV5, (Mouse) Q05144, (Mouse) P60764

          View more View less

          Entrez Gene ID: (Human) 998, (Mouse) 12540, (Rat) 64465, (Human) 5879, (Human) 5880, (Human) 5881, (Mouse) 19353, (Rat) 363875, (Mouse) 19354, (Rat) 366957, (Mouse) 170758, (Rat) 688319

          View more View less

          Function(s)
          GTPase activity obsolete small monomeric GTPase activity protein binding GTP binding protein kinase binding GTP-dependent protein binding thioesterase binding GBD domain binding apolipoprotein A-I receptor binding identical protein binding ubiquitin protein ligase activity mitogen-activated protein kinase kinase kinase binding enzyme binding macromolecular complex binding Rho GDP-dissociation inhibitor binding protein kinase regulator activity calcium-dependent protein binding small GTPase binding histone deacetylase binding ATPase binding
          Process(es)
          chemotaxis actin filament organization establishment or maintenance of cell polarity signal transduction G-protein coupled receptor signaling pathway small GTPase mediated signal transduction positive regulation of cell proliferation regulation of cell shape positive regulation of lamellipodium assembly regulation of cell-substrate adhesion actin cytoskeleton organization cortical cytoskeleton organization regulation of actin cytoskeleton organization regulation of T cell proliferation superoxide anion generation erythrocyte enucleation regulation of mast cell degranulation bone resorption homeostasis of number of cells regulation of respiratory burst regulation of mast cell chemotaxis lymphocyte aggregation positive regulation of neutrophil chemotaxis regulation of neutrophil migration motor neuron axon guidance Wnt signaling pathway Rac protein signal transduction cell projection assembly positive regulation of cell adhesion mediated by integrin intracellular signal transduction respiratory burst cell chemotaxis postsynaptic actin cytoskeleton organization regulation of postsynapse assembly positive regulation of substrate adhesion-dependent cell spreading heart process cardiac neural crest cell migration involved in outflow tract morphogenesis endocytosis phagocytosis, engulfment Golgi organization integrin-mediated signaling pathway anatomical structure morphogenesis regulation of lamellipodium assembly substantia nigra development establishment of cell polarity macrophage differentiation positive regulation of cell growth positive regulation of cell migration positive regulation of pseudopodium assembly negative regulation of protein complex assembly positive regulation of cytokinesis cell junction assembly embryonic heart tube development neuropilin signaling pathway modulation by host of viral process establishment of epithelial cell apical/basal polarity positive regulation of pinocytosis positive regulation of cellular component organization regulation of filopodium assembly positive regulation of filopodium assembly regulation of stress fiber assembly positive regulation of stress fiber assembly establishment of Golgi localization regulation of attachment of spindle microtubules to kinetochore Wnt signaling pathway, planar cell polarity pathway positive regulation of epithelial cell proliferation involved in lung morphogenesis dendritic spine morphogenesis organelle transport along microtubule endothelin receptor signaling pathway regulation of postsynapse organization regulation of hydrogen peroxide metabolic process positive regulation of establishment of protein localization to mitochondrion sprouting angiogenesis cardiac conduction system development protein phosphorylation regulation of mitotic nuclear division nuclear migration Rho protein signal transduction protein localization endosomal transport adherens junction organization establishment or maintenance of apical/basal cell polarity dendritic cell migration positive regulation of catalytic activity positive regulation of MAPK cascade positive regulation of neuron apoptotic process positive regulation of DNA replication positive regulation of JNK cascade filopodium assembly neuron fate determination nucleus localization positive regulation of synapse structural plasticity positive regulation of protein kinase B signaling heart contraction cellular response to interferon-gamma actin filament branching positive regulation of intracellular protein transport cell-cell adhesion regulation of modification of postsynaptic structure regulation of neuron maturation cerebral cortex GABAergic interneuron development regulation of cell morphogenesis neuron projection development homeostasis of number of cells within a tissue neuromuscular process controlling balance neuromuscular process synaptic transmission, GABAergic neuron migration positive regulation of protein phosphorylation auditory receptor cell morphogenesis mast cell chemotaxis sphingosine-1-phosphate signaling pathway epithelial cell morphogenesis hyperosmotic response cytoskeleton organization cell adhesion cell-matrix adhesion enzyme linked receptor protein signaling pathway axon guidance positive regulation of endothelial cell migration regulation of fibroblast migration negative regulation of fibroblast migration positive regulation of cell-substrate adhesion dendrite development cell migration cerebral cortex radially oriented cell migration embryonic olfactory bulb interneuron precursor migration lamellipodium assembly actin filament polymerization regulation of cell migration positive regulation of actin filament polymerization forebrain development positive regulation of microtubule polymerization response to lipopolysaccharide negative regulation of interleukin-23 production substrate adhesion-dependent cell spreading non-canonical Wnt signaling pathway positive regulation of insulin secretion involved in cellular response to glucose stimulus angiotensin-activated signaling pathway engulfment of apoptotic cell cell-cell junction organization regulation of nitric oxide biosynthetic process regulation of JAK-STAT cascade hepatocyte growth factor receptor signaling pathway regulation of neuronal synaptic plasticity anatomical structure arrangement neuron projection morphogenesis dendrite morphogenesis cell motility localization within membrane positive regulation of focal adhesion assembly positive regulation of dendritic spine development regulation of cell adhesion involved in heart morphogenesis regulation of ERK5 cascade cellular response to mechanical stimulus semaphorin-plexin signaling pathway dopaminergic neuron differentiation protein localization to plasma membrane cochlea morphogenesis ruffle assembly positive regulation of ruffle assembly regulation of synaptic vesicle endocytosis positive regulation of bicellular tight junction assembly midbrain dopaminergic neuron differentiation positive regulation of ovarian follicle development response to glucose regulation of exocytosis submandibular salivary gland formation inflammatory response response to wounding ruffle organization positive regulation of Rho protein signal transduction negative regulation of receptor-mediated endocytosis multicellular organismal homeostasis
          It has to be done as per old AB suggested Products section.

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