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          • Primary Antibodies ›
          • RAC1/RAC2/RAC3/CDC42 Antibodies

          Invitrogen

          RAC1/RAC2/RAC3/CDC42 Polyclonal Antibody

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          Cite RAC1/RAC2/RAC3/CDC42 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          RAC1/RAC2/RAC3/CDC42 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          RAC1/RAC2/RAC3/CDC42 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          RAC1/RAC2/RAC3/CDC42 Antibody (PA5-99700) in WB

          Western blot analysis of RAC1/RAC2/RAC3/CDC42 in HepG2 cell lysate. Samples were incubated with RAC1/RAC2/RAC3/CDC42 polyclonal antibody (Product # PA5-99700). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          RAC1/RAC2/RAC3/CDC42 Antibody in Western Blot (WB)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          RAC1/RAC2/RAC3/CDC42 Polyclonal Antibody

          Product Details

          PA5-99700

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human RAC1(Accession P63000), corresponding to amino acid residues M45-A95.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2818633

          Product Specific Information

          Antibody detects endogenous levels of total Rac1/2/3.

          Target Information

          The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Cell division control protein 42 homolog; cell division cycle 42 (GTP binding protein); cell division cycle 42 homolog; Cell migration-inducing gene 5 protein; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); EN-7 protein; G25K GTP-binding protein; growth-regulating protein; GTP binding protein, 25kDa; GTP-binding protein G25K; GX; p21-Rac1; p21-Rac2; p21-Rac3; Protein EN-7; Rac1ins; RAC2; ras-like protein; Ras-like protein TC25; RAS-related C3 botulinum substrate 2; ras-related C3 botulinum toxin substrate; Ras-related C3 botulinum toxin substrate 1; ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); Ras-related C3 botulinum toxin substrate 2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); Ras-related C3 botulinum toxin substrate 3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3); Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); rho family, small GTP binding protein Rac1; rho family, small GTP binding protein Rac3; Small G protein; small GTP binding protein; small GTP binding protein CDC42; unnamed protein product

          View more View less

          Gene Aliases: AI323801; AI452260; AI747189; AL023026; AU018915; CDC42; CDC42Hs; D5Ertd559e; EN-7; G25K; Gx; HSPC022; IMD73A; IMD73B; IMD73C; MIG5; MRD48; p21-Rac1; p21-Rac2; Rac; Rac-1; RAC1; Rac1B; RAC2; RAC3; TC-25; TC25; TKS

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          UniProt ID: (Rat) Q8CFN2, (Mouse) P60766, (Mouse) P63001, (Rat) Q6RUV5, (Mouse) Q05144, (Mouse) P60764

          View more View less

          Entrez Gene ID: (Human) 998, (Rat) 64465, (Mouse) 12540, (Human) 5879, (Human) 5880, (Human) 5881, (Mouse) 19353, (Rat) 363875, (Rat) 366957, (Mouse) 19354, (Mouse) 170758, (Rat) 688319

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          Function(s)
          GTPase activity obsolete small monomeric GTPase activity protein binding GTP binding protein kinase binding GTP-dependent protein binding thioesterase binding GBD domain binding apolipoprotein A-I receptor binding identical protein binding ubiquitin protein ligase activity mitogen-activated protein kinase kinase kinase binding nucleotide binding enzyme binding macromolecular complex binding Rho GDP-dissociation inhibitor binding protein kinase regulator activity calcium-dependent protein binding Rab GTPase binding histone deacetylase binding small GTPase immunoglobulin
          Process(es)
          heart process cardiac neural crest cell migration involved in outflow tract morphogenesis endocytosis phagocytosis, engulfment actin filament organization Golgi organization establishment or maintenance of cell polarity signal transduction integrin-mediated signaling pathway small GTPase mediated signal transduction anatomical structure morphogenesis regulation of lamellipodium assembly positive regulation of lamellipodium assembly substantia nigra development establishment of cell polarity actin cytoskeleton organization macrophage differentiation positive regulation of cell growth positive regulation of cell migration positive regulation of pseudopodium assembly negative regulation of protein complex assembly positive regulation of cytokinesis regulation of actin cytoskeleton organization cell junction assembly embryonic heart tube development neuropilin signaling pathway modulation by host of viral process establishment of epithelial cell apical/basal polarity positive regulation of pinocytosis positive regulation of cellular component organization regulation of filopodium assembly positive regulation of filopodium assembly regulation of stress fiber assembly positive regulation of stress fiber assembly establishment of Golgi localization regulation of attachment of spindle microtubules to kinetochore Wnt signaling pathway, planar cell polarity pathway positive regulation of epithelial cell proliferation involved in lung morphogenesis dendritic spine morphogenesis organelle transport along microtubule endothelin receptor signaling pathway regulation of postsynapse organization positive regulation of substrate adhesion-dependent cell spreading positive regulation of protein phosphorylation sprouting angiogenesis cardiac conduction system development keratinocyte development regulation of mitotic nuclear division nuclear migration metabolic process response to glucose positive regulation of gene expression negative regulation of gene expression single organismal cell-cell adhesion regulation of exocytosis hair follicle morphogenesis keratinization regulation of protein stability positive regulation of peptidyl-serine phosphorylation adherens junction organization cellular protein localization establishment or maintenance of apical/basal cell polarity multicellular organism growth dendritic cell migration regulation of protein catabolic process positive regulation of catalytic activity positive regulation of MAPK cascade regulation of protein heterodimerization activity positive regulation of neuron apoptotic process positive regulation of phosphatidylinositol 3-kinase activity positive regulation of DNA replication regulation of protein kinase activity positive regulation of JNK cascade filopodium assembly neuron fate determination epidermis morphogenesis actin filament bundle assembly regulation of protein metabolic process nucleus localization positive regulation of synapse structural plasticity heart contraction canonical Wnt signaling pathway submandibular salivary gland formation epithelial-mesenchymal cell signaling hair follicle placode formation positive regulation of hair follicle cell proliferation actin filament branching epithelial cell-cell adhesion positive regulation of intracellular protein transport Rho protein signal transduction nervous system development endosomal transport cell differentiation neuron migration sphingosine-1-phosphate signaling pathway inflammatory response cell adhesion cell-matrix adhesion enzyme linked receptor protein signaling pathway motor neuron axon guidance regulation of cell shape response to wounding regulation of hydrogen peroxide metabolic process positive regulation of endothelial cell migration regulation of fibroblast migration negative regulation of fibroblast migration regulation of cell-substrate adhesion cell migration Rac protein signal transduction cell projection assembly lamellipodium assembly actin filament polymerization regulation of cell migration cortical cytoskeleton organization forebrain development ruffle organization response to lipopolysaccharide negative regulation of interleukin-23 production substrate adhesion-dependent cell spreading positive regulation of Rho protein signal transduction intracellular signal transduction non-canonical Wnt signaling pathway positive regulation of insulin secretion involved in cellular response to glucose stimulus superoxide anion generation engulfment of apoptotic cell regulation of nitric oxide biosynthetic process respiratory burst regulation of JAK-STAT cascade hepatocyte growth factor receptor signaling pathway negative regulation of receptor-mediated endocytosis neuron projection morphogenesis cell motility localization within membrane positive regulation of focal adhesion assembly regulation of respiratory burst cell chemotaxis regulation of cell adhesion involved in heart morphogenesis semaphorin-plexin signaling pathway positive regulation of neutrophil chemotaxis ruffle assembly regulation of postsynapse assembly positive regulation of ruffle assembly regulation of synaptic vesicle endocytosis regulation of neutrophil migration positive regulation of bicellular tight junction assembly midbrain dopaminergic neuron differentiation positive regulation of ovarian follicle development chemotaxis regulation of T cell proliferation regulation of mast cell degranulation bone resorption regulation of mast cell chemotaxis lymphocyte aggregation positive regulation of establishment of protein localization to mitochondrion Wnt signaling pathway positive regulation of cell adhesion mediated by integrin postsynaptic actin cytoskeleton organization auditory receptor cell morphogenesis mast cell chemotaxis epithelial cell morphogenesis hyperosmotic response cytoskeleton organization G-protein coupled receptor signaling pathway axon guidance cell proliferation positive regulation of cell-substrate adhesion regulation of neuron maturation dendrite development cerebral cortex radially oriented cell migration embryonic olfactory bulb interneuron precursor migration cerebral cortex GABAergic interneuron development regulation of cell morphogenesis positive regulation of actin filament polymerization cell-cell junction organization anatomical structure arrangement dendrite morphogenesis homeostasis of number of cells within a tissue synaptic transmission, GABAergic cellular response to mechanical stimulus dopaminergic neuron differentiation protein localization to plasma membrane cochlea morphogenesis positive regulation of cell proliferation positive regulation of protein targeting to mitochondrion neuron projection development neuromuscular process controlling balance neuromuscular process
          It has to be done as per old AB suggested Products section.

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