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Product Details
17084-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RAI1 Fusion Protein Ag9046 (1-350 aa encoded by BC021209)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MQSFRERCG FHGKQQNYQQ TSQETSRLEN YRQPSQAGLS CDRQRLLAKD YYNPQPYPSY EGGAGTPSGT AAAVAADKYH RGSKALPTQQ GLQGRPAFPG YGVQDSSPYP GRYAGEESLQ AWGAPQPPPP QPQPLPAGVA KYDENLMKKT AVPPSRQYAE QGAQVPFRTH SLHVQQPPPP QQPLAYPKLQ RQKLQNDIAS PLPFPQGTHF PQHSQSFPTS STYSSSVQGG GQGAHSYKSC TAPTAQPHDR PLTASSSLAP GQRVQNLHAY QSGRLSYDQQ QQQQQQQQQQ QQALQSRHHA QETLHYQNLA KYQHYGQQGQ GYCQPDAAVR TPEQYYQTFS PSSSHSPARS V (1-350 aa encoded by BC021209)
Target Information
This gene is located within the Smith-Magenis syndrome region on chromosome 17. It is highly similar to its mouse counterpart and is expressed at high levels mainly in neuronal tissues. The protein encoded by this gene includes a polymorphic polyglutamine tract in the N-terminal domain. Expression of the mouse counterpart in neurons is induced by retinoic acid. This gene is associated with both the severity of the phenotype and the response to medication in schizophrenic patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Retinoic acid-induced protein 1; Smith-Magenis syndrome chromosome region
Gene Aliases: Gt1; KIAA1820; RAI1; SMCR; SMS
UniProt ID: (Human) Q7Z5J4, (Mouse) Q61818
Entrez Gene ID: (Human) 10743, (Mouse) 19377, (Rat) 303188
skeletal system development
circadian regulation of gene expression
negative regulation of multicellular organism growth
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
rhythmic process
biological_process
Performance Guarantee
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