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Product Details
A304-298A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 166 to 216 of Human RAs-Related Nuclear Protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Zebrafish, X. laevis, X. tropicalis, Chicken, Bovine, Dog and Orangutan
Target Information
Ran (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The Ran protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of Ran requires the presence of regulator of chromosome condensation 1 (RCC1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Androgen receptor-associated protein 24; ARA25; GTP-binding nuclear protein Ran; GTPase Ran; guanosine triphosphatase Ran; member RAS oncogene family; OK/SW-cl.81; OTTHUMP00000166078; OTTHUMP00000166102; RanGTPase; Ras-like protein TC4; Ras-related nuclear protein
Gene Aliases: ARA24; Gsp1; OK/SW-cl.81; RAN; Rasl2-8; TC4
UniProt ID: (Human) Q9CWI7, (Mouse) P62827
Entrez Gene ID: (Human) 5901, (Mouse) 19384
chromatin binding
transcription coactivator activity
GTPase activity
protein binding
GTP binding
GDP binding
protein domain specific binding
protein complex binding
poly(A) RNA binding
dynein intermediate chain binding
androgen receptor binding
importin-alpha family protein binding
pre-miRNA binding
pre-miRNA transporter activity
cadherin binding involved in cell-cell adhesion
nucleotide binding
small GTPase
ribosomal large subunit export from nucleus
ribosomal small subunit export from nucleus
protein import into nucleus, translocation
DNA metabolic process
tRNA export from nucleus
protein export from nucleus
mitotic spindle organization
mitotic nuclear division
signal transduction
small GTPase mediated signal transduction
spermatid development
viral process
hippocampus development
actin cytoskeleton organization
androgen receptor signaling pathway
gene silencing by RNA
positive regulation of protein binding
cellular protein complex localization
pre-miRNA export from nucleus
positive regulation of transcription, DNA-templated
cell division
cellular response to mineralocorticoid stimulus
intracellular transport of virus
cell-cell adhesion
protein localization to nucleolus
ribosomal subunit export from nucleus
protein import into nucleus
transport
intracellular protein transport
nucleocytoplasmic transport
cell cycle
protein transport
cellular protein localization
regulation of protein binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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