PA1-5864 detects Ran in human and Xenopus laevis samples.
PA1-5864 has been successfully used in immunofluorescence, immunoprecipitation and Western blot procedures.
The PA1-5864 immunogen is His-tagged recombinant human Ran protein purified from E. coli.
Ran (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The Ran protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of Ran requires the presence of regulator of chromosome condensation 1 (RCC1).
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Protein Aliases: Androgen receptor-associated protein 24; ARA25; GTP-binding nuclear protein Ran; GTPase Ran; guanosine triphosphatase Ran; member RAS oncogene family; OK/SW-cl.81; ran GTP-binding protein; RanGTPase; Ras-like protein TC4; Ras-related nuclear protein; TC4
Gene Aliases: ARA24; Gsp1; OK/SW-cl.81; RAN; ran-1; RanTC4; TC4; XELAEV_18007741mg; xran