Immunogen sequence: MAEAMDLGKD PNGPTHSSTL FVRDDGSSMS FYVRPSPAKR RLSTLILHGG GTVCRVQEPG AVLLAQPGEA LAEASGDFIS TQYILDCVER NERLELEAYR LGPASAADTG SEAKPGALAE GAAEPEPQRH AGRIAFTDAD DVAILTYVKE NARSPSSVTG NALWKAMEKS SLTQHSWQSL KDRYLKHLRG QEHKYLLGDA PVSPSSQKLK RKAEEDPEAA DSGEPQNKRT PDLPEEEYVK EEIQENEEAV KKMLVEATRE FEEVVVDESP PDFEIHITMC; Positive Samples: MCF7, SW620, 293T, HeLa, NCI-H460, Mouse brain, Mouse kidney; Cellular Location: Chromosome, Cytoplasm, Nucleus, telomere
Differentiated embryo-chondrocyte expressed gene 1 (DEC1) is an important protein involved in embryonic cell differentiation, proliferation, and apoptosis. It has also recently been shown to be regulated by hypoxia. The loss of DEC1 expression may be an early event in the development of lung cancer, while DEC1 may be up-regulated by hypoxia in other cancers and in more extreme hypoxia it may have a role in cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dopamine receptor interacting protein 5; Dopamine receptor-interacting protein 5; hRap1; RAP1 homolog; Repressor/activator protein 1 homolog; telomeric repeat binding factor 2, interacting protein; Telomeric repeat-binding factor 2-interacting protein 1; TERF2-interacting telomeric protein 1; TRF2-interacting telomeric protein 1; TRF2-interacting telomeric protein Rap1; TRF2-interacting telomeric RAP1 protein
Gene Aliases: DRIP5; MNCb-0448; MNCb-0628; PP8000; RAP1; TERF2IP