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Invitrogen
RAP2A/RAP2B Monoclonal Antibody (455410)
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Product Details
MA5-61476
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
455410
Immunogen
E. coli-derived recombinant human Rap2A/B, Met1-Gln183
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
RAP2A and RAP2B are genes encoding small GTPases that belong to the Ras-related protein family. These proteins are involved in various cellular processes, including cell proliferation, differentiation, and migration. RAP2A and RAP2B function as molecular switches, cycling between an active GTP-bound state and an inactive GDP-bound state, thereby regulating signal transduction pathways. They play crucial roles in the organization of the actin cytoskeleton, vesicle trafficking, and cell adhesion. RAP2A and RAP2B are implicated in the regulation of neuronal development and plasticity, and their dysregulation has been associated with neurological disorders. Additionally, abnormal expression or mutations in these genes have been linked to cancer progression, as they can influence tumor cell migration and invasion. Understanding the specific mechanisms and functions of RAP2A and RAP2B is important for elucidating their roles in both normal cellular physiology and disease states. As such, these genes are significant targets in research aimed at developing therapeutic interventions for cancer, neurodegenerative diseases, and other conditions involving cellular signaling abnormalities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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