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Invitrogen
RAP2B Polyclonal Antibody
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Product Details
PA5-101830
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RAP2B(Accession P61225), corresponding to amino acid residues R97-A147.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total RAP2B.
Target Information
This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ras-related protein Rap-2b; small GTP binding protein
Gene Aliases: 4021402C18Rik; AA408554; RAP2B
UniProt ID: (Human) P61225, (Rat) P61227, (Mouse) P61226
Entrez Gene ID: (Human) 5912, (Rat) 170923, (Mouse) 74012
signal transduction
microvillus assembly
platelet activation
negative regulation of cell migration
positive regulation of protein autophosphorylation
Rap protein signal transduction
regulation of protein tyrosine kinase activity
platelet aggregation
establishment of endothelial intestinal barrier
small GTPase mediated signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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