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Proteintech
RASGRP2 Polyclonal Antibody, CoraLite® Plus 488
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FIGURE: 1 / 1
RASGRP2 Antibody (CL488-30189) in Flow
1x10^6 Jurkat cells were intracellularly stained with 0.8 µg Coralite® Plus 488 Rasgrp2 Polyclonal Antibody (CL488-30189) (red), or 0.8 µg CoraLite® Plus 488-conjugated Rabbit IgG control Rabbit PolyAb (CL488-30000) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Product Details
CL488-30189
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RASGRP2 fusion protein Ag32762
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: QYQTEDELY QLSLQREPRS KSSPTSPTSC TPPPRPPVLE EWTSAAKPKL DQALVVEHIE KMVESVFRNF DVDGDGHISQ EEFQIIRGNF PYLSAFGDLD QNQDGCISRE EMVSYFLRSS SVLGGRMGFV HNFQESNSLR PVACRHCKAL ILGIYKQGLK CRACGVNCHK QCKDRLSVEC RRRAQSVSLE GSAPSPSPMH SHHHRAFSFS LPRPGRRGSR PPEIREEEVQ TVEDGVFDIH L
Target Information
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calcium and DAG-regulated guanine nucleotide exchange factor I; calcium and diacylglycerol-regulated guanine nucleotide exchange factor I; CalDAG-GEFI; Cdc25-like protein; F25B3.3 kinase-like protein; guanine exchange factor MCG7; hCDC25L; RAS guanyl nucleotide-releasing protein 2; RAS guanyl releasing protein 2 (calcium and DAG-regulated); RAS guanyl-releasing protein 2; unnamed protein product
Gene Aliases: CALDAG-GEFI; CDC25L; MCG7; RASGRP2
UniProt ID: (Human) Q7LDG7
Entrez Gene ID: (Human) 10235
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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