This target displays homology in the following species: Cow: 93%; Dog: 93%; Guinea Pig: 86%; Human: 86%; Mouse: 100%; Pig: 93%; Rabbit: 93%; Rat: 100%
Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.
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Protein Aliases: COAA; coactivator activator; Paraspeckle protein 2; PSP2; RNA binding motif protein 14; RNA-binding motif protein 14; RNA-binding protein 14; RRM-containing coactivator activator/modulator; synaptotagmin interacting protein; Synaptotagmin-interacting protein; SYT-interacting protein; SYTIP1; TMEM137; transmembrane protein 137
Gene Aliases: 1300007E16Rik; BOS_24993; COAA; p16; p16K; PSP2; RBM14; SIP; Sytip; SYTIP1; TMEM137