Invitrogen

RBPJ Polyclonal Antibody

View all (20) RBPJ antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Tech Support
Datasheet
Protocols
Questions & Answers
Tech Support
Datasheet
Protocols
Questions & Answers
Tech Support

Product Details

PA5-69762

Applications
Tested Dilution
Publications

Western Blot (WB)

1.0 µg/mL
-
Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

synthetic peptide directed towards the middle region of mouse RBPJ

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2689844

Product Specific Information

This target displays homology in the following species: Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%; Zebrafish: 92%

Target Information

CSL plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair. The protein is abundantly expressed in heart and skeletal muscle and expression is increased by passive stretch. Mutations in this gene can lead to X-linked deafness.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: J kappa-recombination signal-binding protein; RBP-J kappa; rbp-jkappa; Recombining binding protein suppressor of hairless

View more View less

Gene Aliases: AI843960; CBF1; Igkjrb; Igkjrb1; Igkrsbp; RBP-J; RBP-J kappa; Rbpj; RBPjk; Rbpsuh

View more View less

UniProt ID: (Mouse) P31266

View more View less

Entrez Gene ID: (Mouse) 19664

View more View less

Function(s)
RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II repressing transcription factor binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding protein complex binding sequence-specific DNA binding protein N-terminus binding DNA-binding transcription factor
Process(es)
negative regulation of transcription from RNA polymerase II promoter angiogenesis somitogenesis epithelial to mesenchymal transition heart looping blood vessel remodeling inflammatory response to antigenic stimulus secondary heart field specification outflow tract morphogenesis endocardium development endocardium morphogenesis epithelial to mesenchymal transition involved in endocardial cushion formation cardiac left ventricle morphogenesis ventricular trabecula myocardium morphogenesis regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter humoral immune response Notch signaling pathway positive regulation of transcription of Notch receptor target heart development positive regulation of cell proliferation negative regulation of cell proliferation auditory receptor cell fate commitment epidermal cell fate specification regulation of gene expression positive regulation of gene expression negative regulation of neuron projection development negative regulation of smooth muscle cell migration pituitary gland development hemopoiesis neuron differentiation B cell differentiation keratinocyte differentiation negative regulation of ossification positive regulation of BMP signaling pathway negative regulation of smooth muscle cell apoptotic process somatic stem cell population maintenance positive regulation of Notch signaling pathway involved in heart induction dorsal aorta morphogenesis atrioventricular canal development defense response to bacterium myeloid dendritic cell differentiation cell fate commitment negative regulation of cell differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter regulation of timing of cell differentiation positive regulation of smooth muscle cell proliferation sebaceous gland development hair follicle maturation artery morphogenesis positive regulation of cardiac muscle cell proliferation Clara cell differentiation labyrinthine layer blood vessel development arterial endothelial cell fate commitment Notch signaling pathway involved in arterial endothelial cell fate commitment regulation of cell adhesion involved in heart morphogenesis determination of heart left/right asymmetry positive regulation of transcription from RNA polymerase II promoter in response to hypoxia blood vessel lumenization interleukin-4 secretion blood vessel endothelial cell fate specification positive regulation of ERBB signaling pathway positive regulation of ephrin receptor signaling pathway positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment positive regulation of cell proliferation involved in heart morphogenesis
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support