This antibody is predicted to react with canine, mouse and rat based on sequence homology.
This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.
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Protein Aliases: Cancer-associated surface antigen RCAS1; Estrogen receptor-binding fragment-associated gene 9 protein; HGNC:3123; Receptor-binding cancer antigen expressed on SiSo cells
Gene Aliases: EB9; EBAG9; PDAF; RCAS1
UniProt ID: (Human) O00559
Entrez Gene ID: (Human) 9166