Proteintech

RENALASE Polyclonal Antibody

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RENALASE Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of ( -20°C Ethanol) fixed HEK-293 cells using 15003-1-AP (RENALASE antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

RENALASE Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human kidney using 15003-1-AP (RENALASE antibody) at dilution of 1:100 (under 40x lens).

RENALASE Antibody in Western Blot (WB) — Mouse small intestine tissue were subjected to SDS PAGE followed by western blot with 15003-1-AP (RENALASE antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

RENALASE Antibody in Immunoprecipitation (IP) — IP result of anti-RENALASE (IP:15003-1-AP, 4ug; Detection:15003-1-AP 1:500) with HEK-293 cells lysate 2000ug.

Product Details

15003-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2400	View 4 publications 4 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	1:50-1:500	-
Immunoprecipitation (IP)	0.5-4.0 µg	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	RENALASE Fusion Protein Ag13061 (1-342 aa encoded by BC005364) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.33 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

This antibody is specific to RNLS.

Immunogen sequence: MAQVLIVGA GMTGSLCAAL LRRQTSGPLY LAVWDKADDS GGRMTTACSP HNPQCTADLG AQYITCTPHY AKKHQRFYDE LLAYGVLRPL SSPIEGMVMK EGDCNFVAPQ GISSIIKHYL KESGAEVYFR HRVTQINLRD DKWEVSKQTG SPEQFDLIVL TMPVPEILQL QGDITTLISE CQRQQLEAVS YSSRYALGLF YEAGTKIDVP WAGQYITSNP CIRFVSIDNK KRNIESSEIG PSLVIHTTVP FGVTYLEHSI EDVQELVFQQ LENILPGLPQ PIATKCQKWR HSQVTNAAAN CPGQMTLHHK PFLACGGDGF TQSNFDGCIT SALCVLEALK NYI (1-342 aa encoded by BC005364)

Target Information

Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Plasma and urine renalase levels and activity during the recovery of renal function in kidney transplant recipients.

Experimental biology and medicine (Maywood, N.J.)

Quelhas-Santos J,Soares-Silva I,Fernandes-Cerqueira C,Simões-Silva L,Ferreira I,Carvalho C,Coentrão L,Vaz R,Sampaio-Maia B,Pestana M

Tue Apr 01 00:00:00 EDT 2014

Renalase deficiency aggravates ischemic myocardial damage.

Kidney international

Wu Y,Xu J,Velazquez H,Wang P,Li G,Liu D,Sampaio-Maia B,Quelhas-Santos J,Russell K,Russell R,Flavell RA,Pestana M,Giordano F,Desir GV

Fri Apr 01 00:00:00 EDT 2011

Catecholamines regulate the activity, secretion, and synthesis of renalase.

Circulation

Li G,Xu J,Wang P,Velazquez H,Li Y,Wu Y,Desir GV

Tue Mar 11 00:00:00 EDT 2008

Catecholamines regulate the activity, secretion, and synthesis of renalase.

Circulation

Li G,Xu J,Wang P,Velazquez H,Li Y,Wu Y,Desir GV

Tue Mar 11 00:00:00 EDT 2008

Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure.

The Journal of clinical investigation

Xu J,Li G,Wang P,Velazquez H,Yao X,Li Y,Wu Y,Peixoto A,Crowley S,Desir GV

Sun May 01 00:00:00 EDT 2005

Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure.

The Journal of clinical investigation

Xu J,Li G,Wang P,Velazquez H,Yao X,Li Y,Wu Y,Peixoto A,Crowley S,Desir GV

Sun May 01 00:00:00 EDT 2005

Bioinformatics

Protein Aliases: alpha-NAD(P)H oxidase/anomerase; FLJ11218; HGNC:25641; MAO-C; mMAO-C; Monoamine oxidase-C; Renalase; renalase, FAD-dependent amine oxidase; rnls

Gene Aliases: 6530404N21Rik; AI452315; AW060440; C10orf59; RENALASE; RGD1309804; RNLS

UniProt ID: (Human) Q5VYX0, (Rat) Q5U2W9

Entrez Gene ID: (Human) 55328, (Rat) 361751, (Mouse) 67795

Function(s)