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Invitrogen
REPIN1 Polyclonal Antibody
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Product Details
PA5-31367
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human REPIN1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.74 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: HeLa.
Predicted reactivity: Mouse (96%), Rat (97%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Replication initiator 1 (REPIN1) is a gene encoding a zinc-finger protein that plays a critical role in various metabolic processes. Located on chromosome 7 in humans, REPIN1 is prominently expressed in liver and adipose tissues. It is associated with the regulation of body weight and triglyceride levels, as evidenced by its locus within a quantitative trait locus (QTL) related to these metabolic traits. The REPIN1 protein is involved in enhancing DNA bending, which is crucial for replication initiation. Studies have shown that deleting REPIN1 in the liver can lead to improved insulin sensitivity and altered lipid metabolism, with secondary effects on adipose tissue. Additionally, REPIN1 is implicated in iron metabolism and apoptosis regulation, further underscoring its multifaceted role in cellular processes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60 kDa origin-specific DNA-binding protein; 60 kDa replication initiation region protein; ATT-binding protein; DHFR oribeta-binding protein RIP60; DNA-binding protein REPIN1; H_DJ0584D14.12; replication initiation region protein (60kD); Zinc finger protein 464; zinc finger protein 464 (RIP60); zinc finger protein AP4
Gene Aliases: AP4; REPIN1; RIP60; Zfp464; ZNF464
UniProt ID: (Human) Q9BWE0
Entrez Gene ID: (Human) 29803
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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