Invitrogen

REXO2 Polyclonal Antibody

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

View all (8) REXO2 antibodies

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Datasheet

Protocols

Questions & Answers

Tech Support

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REXO2 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent staining of REXO2 in human cell line U-251 MG shows positivity in mitochondria. Samples were probed using a REXO2 Polyclonal Antibody (Product # PA5-58395).

REXO2 Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of REXO2 in human parathyroid gland and skeletal muscle tissues using REXO2 Polyclonal Antibody (Product # PA5-58395). Corresponding REXO2 RNA-seq data are presented for the same tissues.

REXO2 Antibody in Western Blot (WB) — Western blot analysis of REXO2 in Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells); Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells). Samples were probed using a REXO2 Polyclonal Antibody (Product # PA5-58395).

REXO2 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of REXO2 demonstrates antibody specificity. Immunohistochemical analysis of REXO2 using anti-REXO2 Polyclonal Antibody (Product # PA5-58395), shows significant staining of REXO2 in human parathyroid gland and shows minimal or weak staining in human human skeletal muscle tissues. The relative expression levels of REXO2 within each tissue is shown using RNA-Seq. {RE}

Product Details

PA5-58395

Applications	Tested Dilution	Publications
Western Blot (WB)	0.04-0.4 µg/mL	-
Immunohistochemistry (IHC)	1:50-1:200	-
Immunocytochemistry (ICC/IF)	0.25-2 µg/mL	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Recombinant protein corresponding to Human REXO2 View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.05 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.2, with 40% glycerol
Contains	0.02% sodium azide
Storage conditions	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID	AB_2646479

Product Specific Information

Immunogen sequence: YRIIDVSTVK ELCRRWYPEE YEFAPKKAAS HRALDDISES IKELQFYRNN IFKKKIDEKK RKIIENGENE KTVS

Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.

Target Information

Nucleases are components of DNA and RNA metabolism that carry out functions in DNA repair, replication, and recombination and in RNA processing and degradation. SFN is a homolog of Orn, a 3-prime-to-5-prime exoribonuclease of E. coli that attacks the free 3-prime hydroxyl group on single-stranded RNA, releasing 5-prime mononucleotides in a sequential manner.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: C11orf61; novel KRAB box domain containing protein; Oligoribonuclease, mitochondrial; reduced expression 2; REX2, RNA exonuclease 2 homolog; RNA exonuclease 2 homolog; Small fragment nuclease

Gene Aliases: 1810038D15Rik; AW107347; CGI-114; Gm13138; OTTMUSG00000010655; REX2; REXO2; RFN; SFN; SMFN

UniProt ID: (Human) Q9Y3B8, (Mouse) Q9D8S4, (Rat) Q5U1X1

Entrez Gene ID: (Human) 25996, (Mouse) 100043034, (Mouse) 104444, (Rat) 300689

Molecular Function: C2H2 zinc finger transcription factor