From BLAST result, this antibody is specific to RFWD3.45 kDa and 55 kDa maybe spliceosome of RFWD3.
This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
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Protein Aliases: E3 ubiquitin-protein ligase RFWD3; RFWD3; ring finger and WD repeat domain 3; RING finger and WD repeat domain-containing protein 3; RING finger protein 201; RNF201
Gene Aliases: BC027246; RFWD3; RGD1305243; RNF201