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Proteintech
RGS2 Polyclonal Antibody
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Product Details
10678-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RGS2 Fusion Protein Ag1066 (1-211 aa encoded by BC007049)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MQSAMFLAV QHDCRPMDKS AGSGHKSEEK REKMKRTLLK DWKTRLSYFL QNSSTPGKPK TGKKSKQQAF IKPSPEEAQL WSEAFDELLA SKYGLAAFRA FLKSEFCEEN IEFWLACEDF KKTKSPQKLS SKARKIYTDF IEKEAPKEIN IDFQTKTLIA QNIQEATSGC FTTAQKRVYS LMENNSYPRF LESEFYQDLC KKPQITTEPH AT (1-211 aa encoded by BC007049)
Target Information
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; Regulator of G-protein signaling 2; regulator of G-protein signaling 2, 24kDa; RGS2
Gene Aliases: G0S8; GIG31; RGS2
UniProt ID: (Human) P41220
Entrez Gene ID: (Human) 5997
regulation of translation
cell cycle
spermatogenesis
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of phospholipase activity
negative regulation of cardiac muscle hypertrophy
positive regulation of microtubule polymerization
negative regulation of MAP kinase activity
positive regulation of GTPase activity
negative regulation of cAMP-mediated signaling
negative regulation of G-protein coupled receptor protein signaling pathway
brown fat cell differentiation
relaxation of cardiac muscle
relaxation of vascular smooth muscle
positive regulation of cardiac muscle contraction
regulation of adrenergic receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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