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Proteintech
RGS2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
10678-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RGS2 Fusion Protein Ag1066 (1-211 aa encoded by BC007049)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MQSAMFLAV QHDCRPMDKS AGSGHKSEEK REKMKRTLLK DWKTRLSYFL QNSSTPGKPK TGKKSKQQAF IKPSPEEAQL WSEAFDELLA SKYGLAAFRA FLKSEFCEEN IEFWLACEDF KKTKSPQKLS SKARKIYTDF IEKEAPKEIN IDFQTKTLIA QNIQEATSGC FTTAQKRVYS LMENNSYPRF LESEFYQDLC KKPQITTEPH AT (1-211 aa encoded by BC007049)
Target Information
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; GIG31; regulator of G-protein signaling 2, 24kDa; RGS2; unnamed protein product
Gene Aliases: G0S8
UniProt ID: (Human) P41220
Entrez Gene ID: (Human) 5997
response to amphetamine
G-protein coupled receptor signaling pathway
spermatogenesis
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of cardiac muscle hypertrophy
positive regulation of neuron projection development
negative regulation of translation
response to ethanol
negative regulation of G-protein coupled receptor protein signaling pathway
negative regulation of JNK cascade
relaxation of cardiac muscle
relaxation of vascular smooth muscle
maternal process involved in female pregnancy
positive regulation of cardiac muscle contraction
negative regulation of cell growth involved in cardiac muscle cell development
regulation of adrenergic receptor signaling pathway
positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
negative regulation of glycine import across plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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