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RGS2 Polyclonal Antibody

View all (9) RGS2 antibodies

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RGS2 Polyclonal Antibody

Product Details

BS-0492R

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human RGS2, amino acids 116-211.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; GIG31; Regulator of G-protein signaling 2; regulator of G-protein signaling 2, 24kDa; regulator of G-protein signaling protein 2; RGS2; unnamed protein product

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Gene Aliases: G0S8; GIG31; GOS8; RGS2

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UniProt ID: (Human) P41220, (Rat) Q9JHX0, (Mouse) O08849

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Entrez Gene ID: (Human) 5997, (Rat) 84583, (Mouse) 19735

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Function(s)
G-protein alpha-subunit binding GTPase activity GTPase activator activity protein binding calmodulin binding adenylate cyclase inhibitor activity beta-tubulin binding molecular_function GTPase-activating protein
Process(es)
response to amphetamine regulation of translation G-protein coupled receptor signaling pathway spermatogenesis regulation of G-protein coupled receptor protein signaling pathway negative regulation of signal transduction negative regulation of cardiac muscle hypertrophy positive regulation of neuron projection development negative regulation of translation response to ethanol negative regulation of G-protein coupled receptor protein signaling pathway negative regulation of JNK cascade brown fat cell differentiation relaxation of cardiac muscle relaxation of vascular smooth muscle maternal process involved in female pregnancy positive regulation of cardiac muscle contraction negative regulation of cell growth involved in cardiac muscle cell development regulation of adrenergic receptor signaling pathway positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway negative regulation of glycine import across plasma membrane biological_process negative regulation of phospholipase activity positive regulation of microtubule polymerization termination of G-protein coupled receptor signaling pathway negative regulation of MAP kinase activity positive regulation of GTPase activity negative regulation of cAMP-mediated signaling cell cycle
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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