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Invitrogen
RGS2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-29708
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human RGS2. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (97%), Rat (97%), Pig (96%), Chicken (81%), Rhesus Monkey (100%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; GIG31; regulator of G-protein signaling 2, 24kDa; RGS2; RGS2; GTPase activating protein for G-alpha subunits; unnamed protein product
Gene Aliases: G0S8; GOS8
UniProt ID: (Human) P41220, (Mouse) O08849
Entrez Gene ID: (Human) 5997, (Mouse) 19735
response to amphetamine
G-protein coupled receptor signaling pathway
spermatogenesis
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of cardiac muscle hypertrophy
positive regulation of neuron projection development
negative regulation of translation
response to ethanol
negative regulation of G-protein coupled receptor protein signaling pathway
negative regulation of JNK cascade
relaxation of cardiac muscle
relaxation of vascular smooth muscle
maternal process involved in female pregnancy
positive regulation of cardiac muscle contraction
negative regulation of cell growth involved in cardiac muscle cell development
regulation of adrenergic receptor signaling pathway
positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
negative regulation of glycine import across plasma membrane
brown fat cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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