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Invitrogen
RGS2 Polyclonal Antibody
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Product Details
PA5-29708
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human RGS2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (97%), Rat (97%), Pig (96%), Chicken (81%), Rhesus Monkey (100%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; Regulator of G-protein signaling 2; regulator of G-protein signaling 2, 24kDa; RGS2
Gene Aliases: G0S8; GIG31; RGS2
UniProt ID: (Human) P41220
Entrez Gene ID: (Human) 5997
regulation of translation
cell cycle
spermatogenesis
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of phospholipase activity
negative regulation of cardiac muscle hypertrophy
positive regulation of microtubule polymerization
negative regulation of MAP kinase activity
positive regulation of GTPase activity
negative regulation of cAMP-mediated signaling
negative regulation of G-protein coupled receptor protein signaling pathway
brown fat cell differentiation
relaxation of cardiac muscle
relaxation of vascular smooth muscle
positive regulation of cardiac muscle contraction
regulation of adrenergic receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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