Immunogen sequence: SYHGDSQHRA AINTYCSLAA CVLTSVAISS ALHKKGKLDM VHIQNATLAG GVAVGTAAEM MLMPYGALII GFVCGIISTL GFVYLTPFLE SRLHIQDTCG INNLHGIPGI IGGIVGAVTA ASASLEVYGK EGLVHSFDFQ GFNGDWTART QGKFQIYGLL VTLAMALMGG IIVGLILRLP FWGQPSDENC FEDAVYWEMP EGNSTVYIPE DPTFKPSGPS VPSVPMVSPL PMASSVPLVP; Positive Samples: BxPC-3, DU145, 293T, Mouse kidney, Rat kidney; Cellular Location: Apical cell membrane, Multi-pass membrane protein
RHCG (Rhesus blood group family type C glycoprotein), also known as RHGK (Rh glycoprotein kidney), PDRC2 (tumor-related protein DRC2) or SLC42A3, is a multi-pass membrane protein with three potential N-glycosylation sites that belongs to the Rh subfamily of the ammonium transporter family. Expressed in a wide variety of tissues with predominant expression in adult and fetal kidney, RHCg localizes to the apical and/or basolateral cell membrane (depending on the species) and is believed to function as a non-erythroid, bidirectional, electroneutral ammonium transporter.
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Protein Aliases: Ammonium transporter Rh type C; Rh family; Rh family type C glycoprotein; Rh family, C glycoprotein; Rh glycoprotein kidney; Rh type C glycoprotein; Rhesus blood group family type C glycoprotein; Rhesus blood group, C glycoprotein; Rhesus blood group-associated C glycoprotein; Rhesus-associated C glycoprotein; Tumor-related protein DRC2
Gene Aliases: BB065800; C15orf6; CDRC2; PDRC2; RHCG; RHGK; SLC42A3
Molecular Function: primary active transporter